Definition of antabuse

Discussion in 'Canada Meds' started by HSBC, 14-Sep-2019.

  1. shveps Guest

    Definition of antabuse


    Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means that many of the effects of a "hangover" are felt immediately after alcohol is consumed. "Disulfiram plus alcohol, even small amounts, produce flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision, and confusion. In severe reactions there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death." In the body, alcohol is converted to acetaldehyde, which is then broken down by acetaldehyde dehydrogenase. If the dehydrogenase enzyme is inhibited, acetaldehyde builds up and causes unpleasant effects. Disulfiram should be used in conjunction with counseling and support. Disulfiram has been studied as a possible treatment for cancer Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to a harmless acetic acid derivative (acetyl coenzyme A). A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.

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    Antabuse Definition Of Democracy OnlinePharmacyworldwidestore best ED products - Generic Levitra, Tadalafil Cialis, Vardenafil levitra with lowest price and high quality Disulfiram - a drug trade name Antabuse used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested. Antabuse. medicament, medication, medicinal drug, medicine - medicine something that treats or prevents or alleviates the symptoms of disease. Translations. Find patient medical information for Antabuse Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

    Disulfiram (tetraethylthiuramdisulfide) was accidentally discovered to combine with ethyl alcohol to produce a noxious effect by Jacobsen and Hald, in Denmark, in 1947. After its therapeutic introduction by Martensen-Larsen in 1948, this chemical compound, with the market name of Antabuse, has been used in the treatment of patients suffering from chronic alcoholism in unknown numbers of thousands. As with any new treatment method, an overly enthusiastic reception occurred, with successes reported in 60% to 80% of the patients so treated and followed for six months to a year. However, the enthusiasm has diminished, until now the recovery rates are about the same as those reported for other therapeutic modalities. Unfortunately, rather than helping those who did not benefit from other techniques, disulfiram works best with those patients who generally do better with any type of treatment. Unlike the other modal verbs, it is only found in the past tense. Therefore, when it is used with do to make negatives and questions, the form of the auxil...

    Definition of antabuse

    Disulfiram Definition of Disulfiram by Merriam-Webster, Antabus - definition of Antabus by The Free Dictionary

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  6. Looking for online definition of Antabuse in the Medical Dictionary? Antabuse explanation free. What is Antabuse? Meaning of Antabuse medical term.

    • Antabuse definition of Antabuse by Medical dictionary.
    • Antabuse Oral Uses, Side Effects, Interactions, Pictures..
    • StCanadianPharmacy Antabuse Definition Of Democracy..

    ANTABUSE. n. the trade name for the drug disulfiram. ANTABUSE "The person was prescribed Antabuse, which is also known as disulfiram. ". Antabuse definition a drug, a brand of disulfiram, used in the treatment of alcoholism, that acts by. Meaning, pronunciation, translations and examples. ANTABUSE noun The noun ANTABUSE has 1 sense 1. a drug trade name Antabuse used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested. Familiarity information ANTABUSE used as a noun is very rare.

     
  7. alisia User

    The first study to compare the efficacy and safety of tamoxifen versus anastrozole in women treated for ductal carcinoma in situ (DCIS) suggests that anastrozole may be the better choice for preventing the escalation of DCIS into invasive cancer. Findings from the multicenter, phase III NRG Oncology/NSABP B-35 trial showed that after an average follow-up of 8.6 years, 114 breast cancers were detected in women taking tamoxifen compared with 84 among women who received anastrozole. Ten-year breast cancer–free survival was estimated to be 93.5% with anastrozole versus 89.2% with tamoxifen; however, a subgroup analysis showed that anastrozole was not superior to tamoxifen in women older than 60 years. Margolese, MD, lead study author and professor of surgical oncology at The Jewish General Hospital, Mc Gill University in Montreal, Canada, presented these late-breaking findings during a press briefing May 30 at the 2015 ASCO Annual Meeting.“The good news is, tamoxifen and anastrozole are both very effective, but it seems that women have better chances of staying well with anastrozole,” said Margolese. “Women should also consider differences in side effects when discussing treatment options with their doctors.”The trial enrolled 3104 postmenopausal women who had been treated with lumpectomy and radiation after a diagnosis of hormone receptor–positive DCIS. Participants were randomly assigned to receive either tamoxifen (20 mg/day) and placebo, or 1 mg of daily anastrozole and placebo. Patients in both arms were eligible to receive the drugs for 5 years. Margolese explained that the study’s primary objective was to decrease the number of breast cancer events, known as a breast cancer–free interval, defined by the researchers as “the time from randomization to any breast cancer event, including local, regional, or distant recurrence or contralateral disease, either invasive or DCIS.”Although both drugs have long been used as hormonal therapy in patients with breast cancer, they have different mechanisms of action. Breast Cancer Arimedex vs. Tamoxifen - WebMD Comparing Recurrence Risk With Anastrozole vs Tamoxifen in. Compare Anastrozole vs Tamoxifen - Treato
     
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