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    Retinoids are a class of vitamin A derivatives has been used in skin care since the ’70s. Changes are, you're familiar with retinoid because it's the active ingredient that's touted in the vast majority of anti-aging products. The most famous product, Retin-A, is made with the retinoid tretinoin. It was developed in the late ’60s by Albert Kligman, Ph. (Chances are, you used it on pimples back in the day.) Kligman and his colleague James Leyden, M. D., a professor of dermatology at the University of Pennsylvania, as an acne treatment and approved by the U. D., noticed that Retin-A also improved wrinkles and skin tone in acne patients. Kligman eventually patented Renova, a tretinoin in an emollient base, which was the first FDA-approved topical treatment for wrinkles and fine lines. Susan Weinkle, a dermatologist in Bradenton, Florida, calls retinoids skin care’s heavy lifters. That was about 18 years ago, and yet retinoids still star in everything from moisturizers and serums to eye and neck creams. “There is not a single class of ingredient that can rival the track record that retinoids have for proven scientific results,” says Macrene Alexiades-Armenakas, Ph. “I tell patients that regardless of how much time or money they have, sunscreen and a retinoid are the most important anti-agers to use,” she says. Do I need a prescription for Retin-A or is there a product over the counter that has a good amount of tretinoin in it? I wouldn't mind going to a dermatologist to get a script but if there is something over the counter I could at least give it a shot to see if it can help some acne breakouts I have been experiencing. I found it confusing because there are a lot of over the counter skin care products that have retinol included in the ingredients. Retinol is similar to Retin-A but they aren't the same thing. From what I understand, retinol is a little bit safer to use and can be used effectively without a doctor's prescription. Retin-A is potentially dangerous and really should not be used without in depth instructions from a medical professional. When I spoke to my doctor about it, he said that the danger in using Retin-A without a prescription is that it is very difficult to tell normal side effects from potentially dangerous ones.

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    The potent Rx creams contain retinoic acid, the active form of vitamin A that immediately binds with receptors on our skin cells, causing them to behave younger and healthier. The question is almost irrelevant (assuming it’s skin-related) because if you’re asking me or any beauty editor with more than five minutes' experience what to do about pretty much any skin issue — acne, fine lines, brown spots, drooping, dullness, dark circles, enlarged pores — retinol will likely be central to the solution. Along with a bunch of other vitamin-A derivatives starting with the letter R, retinol is an example of a retinoid — that’s the catchall term for these A-based formulas, both the over-the-counter (OTC) and prescription varieties. This directive can translate to countless improvements — normalized cell turnover for clear, glowing skin; balanced pigment production for fewer splotches; revved-up collagen synthesis for smoother skin and tighter pores — but it generally comes with an irksome adjustment period. OTC vitamin-A creams, like retinol and retinaldehyde, tend to be weaker because the skin has to convert them to retinoic acid before using them. Speaking from experience, though, that doesn’t mean they can’t take your face off — especially if you’re sensitive. Which is why with any retinoid you have to practice restraint, applying a pea-size drop only one or two nights a week until skin acclimates, and buffering that dose with a squirt of anti-inflammatory serum or lotion (think niacinamide, polyphenols, lipids, ceramides). These are doctors' orders — well-established ones — that I’ve long practiced and preached. Meredith collects data to deliver the best content, services, and personalized digital ads. We partner with third party advertisers, who may use tracking technologies to collect information about your activity on sites and applications across devices, both on our sites and across the Internet. You always have the choice to experience our sites without personalized advertising based on your web browsing activity by visiting the DAA’s Consumer Choice page, the NAI's website, and/or the EU online choices page, from each of your browsers or devices. To avoid personalized advertising based on your mobile app activity, you can install the DAA’s App Choices app here. You can find much more information about your privacy choices in our privacy policy. Even if you choose not to have your activity tracked by third parties for advertising services, you will still see non-personalized ads on our site.

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