Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic treatment is required because of their improved safety and predictable absorption when administered orally. Fluconazole's spectrum of activity includes most Candida species (but not Candida krusei or Candida glabrata), Cryptococcus neoformans, some dimorphic fungi, and dermatophytes, among others. Common uses include: Fungal resistance to drugs in the azole class tends to occur gradually over the course of prolonged drug therapy, resulting in clinical failure in immunocompromised patients (e.g., patients with advanced HIV receiving treatment for thrush or esophageal Candida infection). albicans, resistance occurs by way of mutations in the ERG11 gene, which codes for 14α-demethylase. These mutations prevent the azole drug from binding, while still allowing binding of the enzyme's natural substrate, lanosterol. glabrata is increasing the rate of efflux of the azole drug from the cell, by both ATP-binding cassette and major facilitator superfamily transporters. Development of resistance to one azole in this way will confer resistance to all drugs in the class. Other gene mutations are also known to contribute to development of resistance. Fluconazole is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth. Fluconazole is also used to prevent candidiasis in patients having bone marrow transplants who receive cancer or radiation treatment. This medicine is available only with your doctor's prescription. Apo-metformin buy online Cialis dapoxetine Diflucan how long does it stay in your system Tadalafil drug How is fluconazole used in people with HIV? The Guidelines for the Prevention and Treatment of. Fluconazole is used to treat vaginal yeast infections. It works by stopping the growth of common types of vaginal yeast fungus. This medication belongs to a class of drugs called azole antifungals. When DIFLUCAN is used concomitantly with these or other sulfonylurea oral hypoglycemic agents, blood glucose concentrations should be carefully monitored. Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor. It comes as a tablet or suspension you take by mouth. Fluconazole oral tablet is available as both a generic drug, and as the brand-name drug Diflucan. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Fluconazole is used to prevent and treat candidiasis. This condition is caused by infection with one of the many types of the fungus Examples of candidiasis include vaginal yeast infection, as well as oral yeast infection (thrush). Candidiasis can also cause infections on other parts of your body, including your throat, esophagus, lungs, and blood. Fluconazole what is it for Fluconazole During Pregnancy and Breastfeeding, Fluconazole Oral Uses, Side Effects, Interactions. Valtrex prescribing informationAmoxil overdoseNorvasc side effects in elderlyLasix overdose treatment Fluconazole is an antifungal commonly purchased as Diflucan. It is generally prescribed for candidiasis in the throat, urinary tract, or vagina. If you took an antibiotic before the Diflucan, the bacteria that keeps the fungus in balance were killed off enough to allow the fungus to grow out of hand causing you an infection. Fluconazole what is it - MedHelp. Diflucan Fluconazole Side Effects, Interactions, Warning, Dosage.. Fluconazole eg Diflucan - NetDoctor. Fluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, esophagus tube leading from the mouth to. Fluconazole is an antifungal medicine. It is usually taken as a single 150 mg dose for vaginal thrush. You can take it at any time of day, either before or after a meal. This medication should only be taken. are taking fluconazole, it may affect.