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    The Food and Drug Administration sees no difference between brand-name and generic medications for depression. Most psychiatrists readily prescribe generics as effective copies of the original. That said, it is not at all rare for patients who switch to a generic from a brand-name medication to experience a difference. Sometimes they feel a return of the old sadness, anxiety, and helplessness that the antidepressant helped to lift. Other times, they get an unusual jolt of the same side effects that hit when they began taking the first drug. There’s not been a “systematic problem” with generic antidepressants, says Jonathan Edward Alpert, MD, Ph D, chief of clinical psychiatry at Massachusetts General Hospital in Boston. But doctors need to be vigilant.” There are scattered reports of people experiencing a return of depression symptoms -- or side effects -- when they go on generics. In one recent study, a group of Canadian psychiatrists described seven cases in which patients with depression were taking Paxil or Celexa. Prozac belongs to a group of anti-depressant medications called selective serotonin reuptake inhibitors (SSRIs) which means that it affects the way your brain uses certain mood-boosting chemicals. Prozac or Fluoxetine generic helps free up serotonin, a chemical produced in your brain that regulates mood. Symptoms of depression can be reduced by allowing serotonin to remain in your brain longer. The generic alternative is not manufactured by the company that makes the brand product. Prozac is used to treat mood disorders like major depression and seasonal affective disorder (SAD). These conditions usually develop because of chemical imbalances in the brain and will cause severe emotional distress if left untreated. In fact, their most common symptoms include extreme sadness and hopelessness, which tend to worsen over time.

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