Sildenafil suppository

Discussion in 'Drugs For Sale' started by squirrel, 19-Aug-2019.

  1. murlada New Member

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    About seventeen years ago, after reporting on the benefit of vaginal Sildenafil (Viagra) for women who had implantation dysfunction due to thin endometrial linings, I was proud to announce the birth of the world’s first “It was as far back as 1989 when I first published a study that examined the correlation between the thickness of a woman’s uterine lining (the endometrium), and the subsequent successful implantation of embryos in IVF patients. This study revealed that when the uterine lining measured A “poor” uterine lining is usually the result of the innermost layer of endometrium (the basal or germinal endometrium from which endometrium grows) not being able to respond to estrogen by propagating an outer, “functional,” layer thick enough to support optimal embryo implantation and development of a healthy placenta (placentation). The “functional” layer ultimately comprises 2/3 of the full endometrial thickness and is the layer that sheds with menstruation in the event that no pregnancy occurs. “The Viagra Connection” Treatments such as supplementary estrogen therapy, aspirin administration and/or administration of high dosage gonadotropin fertility drugs, aimed at improving endometrial development have all yielded disappointing results. ) was gaining popularity as a treatment for erectile dysfunction. The mechanism by which it acted was through increasing penile blood flow through increasing nitric oxide activity. This prompted me to investigate whether Viagra administered vaginally, might similarly improve uterine blood flow and in the process cause more estrogen to be delivered to the basal endometrium and thereby increase endometrial thickening. My doctor has prescribed me Viagra suppositories to treat a thin uterine lining. I just heard back from the retail pharmacy and it is $4,500! Does anyone have any experience with this medication and know if fertility pharmacies carry it? I have left messages for a few specialty pharmacies. I thought while I was waiting, I would check to see if anyone has any advice. My insurance won't cover Viagra for women (they said for men, they only cover 6 pills every 30 days). I thought I was done with all of the expensive medications so this caught me off guard! I tried searching old threads for this, but couldn't find any current info.

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    Sildenafil vaginal suppositories Preparation, characterization, in vitro and in vivo evaluation. Article PDF Available in Drug Development and Industrial. Oct 12, 2017. You can get alprostadil injected directly into the penis. Or you can use it as suppository, placing it into the opening at the tip of the penis. Each patient then received a combination of sildenafil suppositories 25 mg intravaginally four times per day and oestradiol valerate 4 mg i.m. twice per week for.

    Being unaccustomed to sticking my fingers up my twat (I’m part of the Tampax generation) - I found it difficult to shove a Viagra suppository far enough into my vagina so that it did not fly out – at high velocity, across the room - the moment I sneezed or sat down. I even had to use those Viagra suppositories during my period. It created a revolting, creamy, nasty mess – like bloody cake frosting - on my maxi-pads. And when inserting them, I’d get the bloody mess on my fingers and under my fingernails. take one orally by accident - too many damn pills to keep track of - and ended up calling the clinic's after-hours RE Fellow in a complete and utter panic, convinced I was going to die. The Fellow laughed at me and assured me taking progesterone orally was harmless but completely ineffective.) But instead of swallowing the progesterone capsules with a glass of water, you’d put them where the sun don’t shine. That boosts blood flow throughout the body, including the penis, so it helps men with ED have an erection. You can get alprostadil injected directly into the penis. Or you can use it as suppository, placing it into the opening at the tip of the penis. Injectable alprostadil is sold under the brand names Caverject, Edex, and Prostin VR. The suppository form is called “MUSE” (which stands for Medicated Urethral System for Erection). Alprostadil should only be used in men with erectile dysfunction. It’s not used properly, it can permanently damage the penis.

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    The route less traveled - UF Health Professionals, Alprostadil Injection and Suppository for Erectile Dysfunction - WebMD

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  5. Drug Dev Ind Pharm. 2014 Jun;406803-12. doi 10.3109/03639045.2013.788011. Epub 2013 Jun 19. Sildenafil vaginal suppositories preparation.

    • Sildenafil vaginal suppositories preparation, characterization. - NCBI.
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    INTERVENTIONS Patients underwent IVF using a long GnRH-a protocol with the addition of sildenafil vaginal suppositories 25 mg, 4 times per day for 3-10. Apr 11, 2016. We enlisted the services of a compound pharmacy to produce vaginal Viagra suppositories. Initially, four 4 women with chronic histories of. Author Allen Loyd V Jr, Year 2005, Abstract A formulation for preparing Sildenafil Vaginal Suppository. Includes ingredients, method of preparation, discussion.

     
  6. salelink Moderator

    Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The stated frequencies of adverse reactions represent the proportion of individuals who experienced, at least once, a treatment-emergent adverse reaction of the type listed. A reaction was considered treatment-emergent if it occurred for the first time or worsened while receiving therapy following baseline evaluation. Reactions reported during the studies were not necessarily caused by the therapy, and the frequencies do not reflect investigator impression (assessment) of causality. — The data described below reflect exposure to duloxetine in placebo-controlled trials for MDD (N=3779), GAD (N=1018), OA (N=503), CLBP (N=600), DPNP (N=906), and another indication (N=1294). The population studied was 17 to 89 years of age; 65.7%, 60.8%, 60.6%, 42.9%, and 94.4% female; and 81.8%, 72.6%, 85.3%, 74.0%, and 85.7% Caucasian for MDD, GAD, OA and CLBP, DPNP, and another indication, respectively. Most patients received doses of a total of 60 to 120 mg per day Pediatric use information for patients ages 7 to 17 years is approved for Eli Lilly and Company, Inc.'s CYMBALTA® (duloxetine) delayed-release capsules. DailyMed - DULOXETINE- duloxetine capsule, delayed release Duloxetine generic pictures UsaBuyPills2018 Pictures of Cymbalta -
     
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