Valtrex pregnancy category

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  1. Temych Well-Known Member

    Valtrex pregnancy category


    24 hours after lesion onset) Suppressive therapy (immunocompetent patients): 1 g/day PO Suppressive therapy (immunocompetent patients with ≤9 recurrences annually): 500 mg/day PO; transmission reduction for source partner, 500 mg/day PO Suppressive therapy (HIV-infected patients): 500 mg PO q12hr Thrombotic thrombocytopenic purpura (TTP)/hemolytic uremic syndrome (HUS) reported in patients with advanced HIV disease and in allogenic bone marrow transplant and renal transplant recipients Acute renal failure (ARF) may occur, especially in elderly patients or those with underlying renal impairment receiving higher than recommended doses; use with caution in patients with renal impairment, the elderly, and/or patients receiving nephrotoxic drugs Treatment should begin with the earliest symptom (tingling, burning, itching) in cold sores; for genital herpes, it should begin at the first signs and symptoms (within 72 hours of onset of first diagnosis or 24 hours of onset of recurrent episodes); for herpes zoster, it should begin within 72 hours of onset of rash; for chicken pox, it should begin with the earliest sign or symptom Central nervous system (CNS) effects may occur (eg, agitation, hallucinations, confusion, encephalopathy); risk of CNS adverse effects is higher in elderly patients Adequately hydrate patient; decreased precipitation in renal tubules may occur Metabolized by liver; valacyclovir is rapidly and nearly completely converted to acyclovir and L-valine via first-pass effect; acyclovir is hepatically metabolized to a very small extent by aldehyde oxidase and by alcohol and aldehyde dehydrogenase (inactive metabolites) The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. It is also used to treat chickenpox and cold sores in children. In your body, valacyclovir becomes the anti-herpes medicine, acyclovir. Although valacyclovir will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores heal faster. Valacyclovir is available only with your doctor's prescription. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.

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    Nov 14, 2014. Valtrex is the brand name for valacyclovir, an antiviral drug used to treat. to harm an unborn child but discuss a pregnancy with your doctor. Suppressive Treatment for Genital Herpes in Pregnancy. Acyclovir Zovirax and valacyclovir Valtrex are the drugs most commonly used for. Valtrex pregnancy category - Is there a difference between valtrex and acyclovir - Valacyclovir hcl dosage for genital herpes Posted on April 6, 2017 After 5 months in Australia it is finally time to return to La Paz and Sonrisa – lots of changes as we move ashore and get Sonrisa ready for charters.

    ABSTRACT QUESTION One of my patients is a pregnant woman in her first trimester with a history of recurrent genital herpes. She is concerned about whether use of her antiviral medication will adversely affect her baby. ANSWER Studies have shown that the use of acyclovir or valacyclovir is not associated with an increase in birth defects. Limited data exist for famciclovir and therefore it would not be considered a first-line choice for treatment of herpes during pregnancy. QUESTION L'une de mes patientes enceintes en est à son premier trimestre de grossesse et elle a des antécédents d'herpès génital récurrent. Elle se demande si l'utilisation de ses médicaments antiviraux pourrait nuire à son bébé. RPONSE Des études ont démontré que l'utilisation de l'acyclovir ou du valacyclovir n'est pas associèe à une augmentation des anomalies congénitales. Les données concernant le famciclovir sont limitées et ce médicament ne devrait donc pas étre considéré comme choix de traitement de première intention pour l'herpès durant la grossesse. Neonatal HSV infections are considered more serious compared with adult infections, having consequences that include the following: skin, eye, and mouth infections; central nervous system diseases; disseminated infections; and death. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of valacyclovir in children below 12 years of age with cold sores, and children below 2 years of age with chickenpox. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of valacyclovir in the elderly. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose of patients receiving valacyclovir. Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

    Valtrex pregnancy category

    Valacyclovir Valtrex Use During Pregnancy -, Genital Herpes Suppressive Treatment in Pregnancy - Healthline

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  4. Oct 10, 2017. FDA Drug Category B. Summary Recommendations Valacyclovir is prescribed for the treatment of the herpes simplex virus. The virus can.

    • Valacyclovir During Pregnancy and Breastfeeding.
    • Valtrex pregnancy category - Is there a difference between valtrex and..
    • VALTREX* Tablets - GSK.

    The U. S. Food and Drug Administration considers acyclovir, valacyclovir, and famciclovir category B drugs in pregnancy, but there are few data on early pregnancy exposure. Pasternak and Hviid investigated the risk of major birth defects in the infants of mothers who took antiviral medication in their first trimester. Medscape - Herpes simplex, zoster-specific dosing for Valtrex valacyclovir. contraindications, pregnancy & lactation schedules, and cost information. Jun 9, 2015. Valtrex - Get up-to-date information on Valtrex side effects, uses. This medication falls into category B. There are no well-done studies that.

     
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    Antibiotic Class: Quinolone Antimicrobial Spectrum: Gram-positive: methicillin-susceptible Staphylococcus aureus (MSSA) (lowest quinolone activity vs. MSSA), Streptococcus pneumoniae Gram-negative: Enterobacteriaceae, H. Pharmacokinetics: Dose of 750mg; Cmax: 3.5mg/ml; Volume of distribution: 3.2 L/kg; Table 2 & Table 3 Adverse Effects: CNS: headache, insomnia, dizziness; hallucinations, depression, psychotic reactions (rare) Connective tissue: tendon injury Renal: interstitial nephritis Cardiovascular: QTC prolongation, torsades de pointes, arrhythmias Dosage: Tablets: 100mg, 250mg, 500mg, 750mg, 500mg extended release tabs, 1000mg extended release tablets IV: 200mg, 400mg Suspension: 250mg/5ml and 500mg/5ml (both in 100ml bottles) Adult patients: Lower respiratory tract infections: 500-750mg PO q12h / 400mg q8-12h IV x 7-14 days Acute sinusitis: 500mg PO q12h / 400mg q12h IV x 10 days Nosocomial pneumonia: 400mg IV q8h x 10-14 days Uncomplicated UTI: 250mg PO q12h x 3 days 500mg extended release tablets q24h Complicated UTI/Pyelonephritis: 500mg PO q12h / 400mg IV q12h x 7-14 days 1000mg extended release tablets q24h Prostatits: 500mg PO q12h / 400mg IV q12h x 28 days Uncomplicated gonococcal infections: 500mg PO x 1 dose Chancroid: 500mg PO q12h x 3 doses Uncomplicated skin/skin structure: 500-750mg PO q12h x 7-14 days / 400mg IV q8-12h Intra-abdominal infections: 500mg PO q12h x 7-14days / 400mg IV q12h Infectious diarrhea: 500mg q12h x 3-5 days (current recommendations) 500mg PO q12h x 5-7 days (labeled) Inhalational anthrax (post-exposure): 500mg PO q12h x 60 days Febrile neutropenia: 400mg IV q8h Pediatrics: Complicated UTI/Pyelonephritis: 6-10mg/kg not to exceed 400mg per dose q8h x 10-21 days 10-20mg/kg not to exceed 750mg per dose q12h x 10-21 days Inhalational anthrax (post-exposure): 10mg/kg not to exceed 400mg per dose q12h x 60 days 15mg/kg not to exceed 500mg per dose q12h x 60 days Table 4 Disease state based dosing: Renal failure: IV: Cr Cl 30 m L/min or greater, give usual dose; Cr Cl 5-29 m L/min, 200-400 mg IV every 18-24 hr ORAL: Cr Cl greater than 50 m L/min, give usual dose; Cr Cl 30-50 m L/min, 250-500 mg every 12 hr; Cr Cl 5-29 m L/min, 250-500 mg every 18 hr Hepatic failure: No dosing changes recommended at this time. Pharmacodynamics: Fluoroquinolones produce both (peak: MIC), and a combination of concentration and time-dependent killing (AUC: MIC). maltophilia Atypicals: Legionella pneumophilia Mechanism of Action: Inhibition of topoisomerase (DNA gyrase) enzymes, which inhibits relaxation of supercoiled DNA and promotes breakage of double stranded DNA. Pharmacokinetics of ciprofloxacin after oral and intravenous. Ciprofloxacin - GlobalRPH Ciprofloxacin - Wikipedia
     
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