Megalis 20 is known as the highest available dose out of all erectile dysfunction medications. This high dosage can be consumed when the patient has consumed the lower dose and have tolerated it well, but it has not produced some sufficient response. Impotent men consuming such composed medicine will tend to start on the lower dose, and only have their dosage increased by their prescriber if it does not provide any desired results. This is one of the most popular medicines that are known for lasting longer than other pills. Thus, for delivering a long-lasting effectiveness, this in Megalis 20 is used for treating Erectile Dysfunction (impotence) by inhibiting PDE5 and having a longer duration of action for approx. This medicine is also popularly known as "The Weekend Pill" due to the long-lasting effects and it is popular in many areas of the US and across the world. Note that the ED treating medicine works over impotence only in presence of complete sexual stimulation. 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