Clonidine withdrawal syndrome

Discussion in 'Online Canadian Pharmacy' started by Boogabear, 08-Sep-2019.

  1. Iluha New Member

    Clonidine withdrawal syndrome


    Clonidine, sold as the brand name Catapres among others, is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, drug withdrawal (alcohol, opioids, or smoking), menopausal flushing, diarrhea, and certain pain conditions. Clonidine is used to treat high blood pressure, attention deficit hyperactivity disorder (ADHD), drug withdrawal (alcohol, opioids, or smoking), menopausal flushing, diarrhea, and certain pain conditions. It can alleviate opioid withdrawal symptoms by reducing the sympathetic nervous system response such as tachycardia and hypertension, as well as reducing sweating, hot and cold flashes, and general restlessness. Clonidine also has several off-label uses, and has been prescribed to treat psychiatric disorders including stress, sleep disorders, and hyperarousal caused by post-traumatic stress disorder, borderline personality disorder, and other anxiety disorders. Clonidine has also been used to treat refractory diarrhea associated with irritable bowel syndrome, fecal incontinence, diabetes, withdrawal-associated diarrhea, intestinal failure, neuroendocrine tumors and cholera. The reduction in circulating norepinephrine by clonidine was used in the past as an investigatory test for phaeochromocytoma, which is a catecholamine-synthesizing tumour, usually found in the adrenal medulla. In a clonidine suppression test plasma catecholamine levels are measured before and 3 hours after a 0.3 mg oral test dose has been given to the patient. Clonidine belongs to a class of drugs called central alpha-adrenergic agonists. In the United States, clonidine tablets are sold under the brand name Catapres and clonidine skin patches are sold under the brand name Catapres-TTS. There is also an injectable form that is administered directly into the spinal cord for the treatment of postoperative pain. Clonidine tablets and patches are approved by the United States Food and Drug Administration (FDA) for the treatment of high blood pressure. However, clonidine has been found to be useful in the treatment of alcohol, opiate, and nicotine withdrawal syndromes, attention-deficit/hyperactivity disorder (ADHD), and Tourette's syndrome, one of the tic disorders . Clonidine was synthesized in 1960s and was initially tested as a nasal decongestant. In the United States, clonidine was first used to treat hypertension although it has also been investigated for treatment of different neuropsychiatric disorders. Clonidine works on specific nerve cells in the brain that are responsible for lowering blood pressure, slowing heart rate, and decreasing the body's reaction to the withdrawal of chemicals like alcohol, opiates, cocaine, and nicotine.

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    Restlessness or RLS Restlessness or RLS restless leg syndrome are additional withdrawal symptoms related to spikes in sympathetic nervous system activation following clonidine cessation. The restlessness or RLS may cause you to pace around or fidget more than you usually do. For me, clonidine should be a very, very *last resort* medication for opiate withdrawal -- i.e. if absolutely nothing else is available. The reason is, clonidine actually intensifies one of the worst opiate withdrawal symptoms mental depression & weakness. Clonidine is used to treat withdrawal symptoms, but when abused it can cause the same symptoms it can normally treat.

    Clonidine is often used to help alleviate uncomfortable withdrawal symptoms caused by an opioid addiction. It works by blocking chemicals in the brain that trigger sympathetic nervous system activity, reducing the length of the detox process. Clonidine belongs to a class of medicines known as antihypertensives. It is frequently prescribed to help with the symptoms of opioid withdrawal. Clonidine works by blocking chemicals in the brain that trigger sympathetic nervous system activity. This reduces uncomfortable symptoms of opioid detoxification, such as sweating, hot flashes, watery eyes and restlessness. Additionally, clonidine has been known to help lower anxiety and may even cut time off the detox process. Clonidine is a drug that is used primarily to treat high blood pressure by acting as an α2 adrenergic agonist. It also has been approved to treat ADHD (attention-deficit hyperactivity disorder), anxiety disorders, and panic attacks. In some cases it is even used to help manage chronic pain and is a commonly used drug to help ease opiate withdrawal symptoms. Other uses of Clonidine include: helping treat the “tics” in Tourette syndrome, alcohol withdrawal, nicotine withdrawal, migraine headaches, insomnia, sleep disorders and restlessness. Most medical professionals consider this drug pretty safe for treating a variety of conditions. In fact, many doctors prefer Clonidine to a more powerful benzodiazepine drug like Xanax due to the fact that it is effective at easing symptoms of anxiety and it isn’t associated with long term memory impairment and/or dementia. I have personally taken this drug for anxiety and in my experience, it has worked pretty well at easing symptoms.

    Clonidine withdrawal syndrome

    Clonidine For Opiate Withdrawal Symptoms, Clonidine systemic User Reviews for Opiate

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  7. Nov 25, 1976. Correspondence from The New England Journal of Medicine — Symptoms of Clonidine Withdrawal after 17 Days.

    • Symptoms of Clonidine Withdrawal after 17 Days NEJM.
    • Clonidine Detox Centers – Clonidine Withdrawal Treatment Facilities.
    • Clonidine - Wikipedia.

    While clonidine does not have many FDA-approved uses, the medication is often used off label. The drug is prescribed to treat hot flashes, restless leg syndrome, Tourette’s syndrome, and opioid withdrawal. The drug is one of the few medications routinely used in opioid withdrawal that is not, itself, a full or partial opioid-agonist. Clonidine is a central alpha adrenergic agonist which can be used to treat the opiate withdrawal syndrome. It has been used in many controlled trials and a substantial body of research evidence is available about its effectiveness in this role. Clonidine, along with other medications, is sometimes used during opiate withdrawal to relieve withdrawal symptoms and facilitate the overall detox process. It can reduce anxiety, agitation, muscle pain, cramping, sweating, and runny nose during opiate withdrawal. Find out more including the typical recommended dosage.

     
  8. Vasya_P XenForo Moderator

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