Ordering prescription drugs online and getting them delivered by mail may be legal if certain requirements are met. These requirements range from ones you must fulfill to those that must be met by the business you're ordering from. Learn the steps to ensure you are ordering from a legitimate online pharmacy with a valid prescription. federal law, in order to sell you a prescription drug, any pharmacy must be able to prove that you, as the purchaser, has a relationship with the doctor who writes the prescription. To purchase a prescription drug, the most important requirement is that you have a real prescription to give to the pharmacy. The pharmacy must require your doctor's signature on a prescription. Some online pharmacies will tell you that their in-house "doctor" can write you a prescription without seeing you in person. This is a clear violation of the law as the "doctor" has no basis by which to make a diagnosis. 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