Sertraline hydrochloride msds

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  1. Grisly New Member

    Sertraline hydrochloride msds


    Sertraline exhibits better selectivity for inhibiting 5-HT uptake relative to NE uptake than fluvoxamine, zimelidine, norzimelidine, fluoxetine or chlorimipramine. However, Sertraline is less selective for blocking 5-HT uptake, relative to DA uptake than these agents. Sertraline HCl (32μmol/kg i.p.) inhibits serotonin uptake into striatal synaptosomes from rats by more than 50%. Sertraline HCl is 6 times more potent than chlorimipramine and 60 times more potent than amitriptyline in reversing the 5-HT depletion elicited by PCA. Acute and repeated dosing of sertraline decreased serotonin content of whole blood. Sertraline HCl strongly reduces immobility of mice in the Porsolt swim test for antidepressants. After repeated dosing in rats, sertraline HCl diminishes the cyclic AMP response of limbic forebrain adenylate cyclase to norepinephnne, as well as the binding of [ Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. * Disclaimer: The Harmonized System (HS) code provided on this webpage are for information purposes only and are subject to change without notice. USP is not responsible for the accuracy or completeness of the information furnished. The exporter and/or importer of record is responsible for determining the accuracy of items at the time of export/import per U.

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    Chemsrc provides Sertraline hydrochlorideCAS#79559-97-0 MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of. WeightMW 342.69. Sertraline HCl is a 5-HT antagonist with Ki of 13 nM. S405301, S405302. Purity 99.97 %; DMSO Solubility 69 mg/mL 201.34 mM. Sertraline 50 mg and 100 mg Tablets. containing sertraline as sertraline hydrochloride. Presentation. SETRONA 100 mg tablets are white film-coated caplet.

    Sertraline hydrochloride belongs to a class of antidepressant agents known as selective serotonin-reuptake inhibitors (SSRIs). Despite distinct structural differences between compounds in this class, SSRIs possess similar pharmacological activity. As with other antidepressant agents, several weeks of therapy may be required before a clinical effect is seen. SSRIs are potent inhibitors of neuronal serotonin reuptake and terminal autoreceptors. The overall clinical effect of increased mood and decreased anxiety is thought to be due to adaptive changes in neuronal function that leads to enhanced serotonergic neurotransmission. Side effects include dry mouth, nausea, dizziness, drowsiness, sexual dysfunction and headache (see Toxicity section below for a more detailed listing of side effects). Sertraline HCl is a selective and potent inhibitor of ST (serotonin transporter), increasing availability of serotonin in the brain. Sertraline displays antiproliferative activity on human colorectal carcinoma cells.

    Sertraline hydrochloride msds

    Sertraline Hydrochloride - LKT Labs, Sertraline HCl 5-HT Receptor inhibitor Read Reviews & Product.

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  3. Sertraline Hydrochloride Racemic Mixture 30 mg 1RS,4RS-4-3,4-Dichlorophenyl-N-methyl-1,2,3. SDS, View. USP Certificate for Current Lot, View.

    • Sertraline Hydrochloride Racemic Mixture - Upcoming System Outage..
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    Apr 16, 2015. Buy Sertraline hydrochloride CAS 79559-97-0, a selective ST inhibitor, from Santa Cruz. Citations; SDS & Certificate of Analysis. Material Safety Data Sheet. 1R,4S Sertraline Hydrochloride sc-208895. Hazard Alert Code Key EXTREME. HIGH. MODERATE. LOW. Section 1 - CHEMICAL. Material Name Sertraline Hydrochloride Capsules. Details of the Supplier of the Safety Data Sheet. 2. HAZARDS. pfizer-MSDS@

     
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